5LMG

Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM10 peptide (region 954-970)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA topoisomerase 2-associated protein PAT1	polymer	369	42282.4	2	UniProt (P25644) Pfam (PF09770)	Saccharomyces cerevisiae (Baker's yeast)	Decapping activator and translational repressor PAT1,Topoisomerase II-associated protein PAT1,mRNA turnover protein 1
2	C, D (C, D)	mRNA decapping protein 2	polymer	14	1557.8	2	UniProt (B3LNX5) UniProt (by SIFTS) (P53550)	Saccharomyces cerevisiae	DCP2 decapping factor
3	E, F, G, H, I... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	13	Chemie (EDO)
4	N (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	O (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
6	T, U (A, B)	water	water		18.0	196	Chemie (HOH)

Sequence modifications

A, B: 435 - 796 (UniProt: P25644)

PDB	External Database	Details
Met 428	-	initiating methionine
His 429	-	expression tag
His 430	-	expression tag
His 431	-	expression tag
His 432	-	expression tag
His 433	-	expression tag
His 434	-	expression tag
Ala 706	Gln 706	engineered mutation
Ala 713	Leu 713	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	87680.4
Non-Polymers*	Number of molecules	15
	Total formula weight	953.3
All*	Total formula weight	88633.8

*Water molecules are not included.