5LL8
Human Carbonic Anhydrase II in complex with aliphatic Benzenesulfonamide inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 265 | 29806.6 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | B, C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | G (A) | 4-butylbenzenesulfonamide | non-polymer | 213.3 | 1 | Chemie (6YP) | |||
| 5 | H (A) | (4-CARBOXYPHENYL)(CHLORO)MERCURY | non-polymer | 357.2 | 1 | Chemie (BE7) | |||
| 6 | I (A) | MERCURY (II) ION | non-polymer | 200.6 | 1 | Chemie (HG) | |||
| 7 | J (A) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29806.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1204.8 | |
| All* | Total formula weight | 31011.4 |
