5LHU
ATP Phosphoribosyltransferase from Mycobacterium tuberculosis in complex with the allosteric inhibitor L-Histidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP phosphoribosyltransferase | polymer | 294 | 31686.0 | 1 | UniProt (P9WMN1) Pfam (PF01634) Pfam (PF08029) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | ATP-PRTase |
| 2 | B (A) | HISTIDINE | non-polymer | 156.2 | 1 | Chemie (HIS) | |||
| 3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | I (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | J (A) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 1 - 284 (UniProt: P9WMN1)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | initiating methionine |
| Ala -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31686.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 824.6 | |
| All* | Total formula weight | 32510.7 |
