5LHU

ATP Phosphoribosyltransferase from Mycobacterium tuberculosis in complex with the allosteric inhibitor L-Histidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ATP phosphoribosyltransferase	polymer	294	31686.0	1	UniProt (P9WMN1) Pfam (PF01634) Pfam (PF08029) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	ATP-PRTase
2	A	HISTIDINE	non-polymer		156.2	1	Chemie (HIS)
3	A	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	86	Chemie (HOH)

Sequence modifications

A: 1 - 284 (UniProt: P9WMN1)

PDB	External Database	Details
Met -9	-	initiating methionine
Ala -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ala -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31686.0
Non-Polymers*	Number of molecules	8
	Total formula weight	824.6
All*	Total formula weight	32510.7

*Water molecules are not included.