5LBW
Structure of the human quinone reductase 2 (NQO2) in complex with volitinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ribosyldihydronicotinamide dehydrogenase [quinone] | polymer | 237 | 26775.4 | 2 | UniProt (P16083) Pfam (PF02525) | Homo sapiens (Human) | NRH dehydrogenase [quinone] 2,NRH:quinone oxidoreductase 2,Quinone reductase 2,QR2 |
| 2 | C, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 4 | E, H (A, B) | volitinib | non-polymer | 345.4 | 2 | Chemie (V0L) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 230 (UniProt: P16083)
| PDB | External Database | Details |
|---|---|---|
| His 231 | - | expression tag |
| His 232 | - | expression tag |
| His 233 | - | expression tag |
| His 234 | - | expression tag |
| His 235 | - | expression tag |
| His 236 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53550.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2392.6 | |
| All* | Total formula weight | 55943.4 |
