5LAR
Crystal structure of p38 alpha MAPK14 in complex with VPC00628
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 14 | polymer | 361 | 41395.2 | 1 | UniProt (P47811) Pfam (PF00069) In PDB | Mus musculus (Mouse) | MAPK 14,CRK1,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha |
| 2 | A | 5-azanyl-~{N}-[[4-[[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide | non-polymer | 502.6 | 1 | Chemie (6SH) | |||
| 3 | water | water | 18.0 | 407 | Chemie (HOH) |
Sequence modifications
A: 1 - 360 (UniProt: P47811)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41395.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 502.6 | |
| All* | Total formula weight | 41897.8 |
