5L98
Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain adjacent to zinc finger domain protein 2B | polymer | 116 | 13531.6 | 1 | UniProt (Q9UIF8) Pfam (PF00439) | Homo sapiens (Human) | hWALp4 |
| 2 | B (A) | ~{N}-[(1~{S})-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-2-methyl-pyridin-3-amine | non-polymer | 270.3 | 1 | Chemie (6RY) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A: 1858 - 1971 (UniProt: Q9UIF8)
| PDB | External Database | Details |
|---|---|---|
| Ser 1856 | - | expression tag |
| Met 1857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13531.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 394.5 | |
| All* | Total formula weight | 13926.0 |
