5L4Z

Crystal structure of enzyme in purine metabolism

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cytosolic purine 5'-nucleotidase	polymer	555	64117.9	1	UniProt (P49902) Pfam (PF05761) In PDB	Homo sapiens (Human)	Cytosolic 5'-nucleotidase II
2	A	GLYCEROL	non-polymer		92.1	13	Chemie (GOL)
3		water	water		18.0	210	Chemie (HOH)

Sequence modifications

A: 1 - 536 (UniProt: P49902)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Trp 238	Arg 238	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	64117.9
Non-Polymers*	Number of molecules	13
	Total formula weight	1197.2
All*	Total formula weight	65315.2

*Water molecules are not included.