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5L3E

LSD1-CoREST1 in complex with quinazoline-derivative reversible inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ALysine-specific histone demethylase 1Apolymer73081279.41UniProt (O60341)
Pfam (PF04433)
Pfam (PF01593)
In PDB
Homo sapiens (Human)BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2
2BREST corepressor 1polymer17820244.81UniProt (Q9UKL0)
Pfam (PF20878)
Pfam (PF00249)
In PDB
Homo sapiens (Human)Protein CoREST
3AFLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
4AN~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6,7-dimethoxyquinazoline-2,4-diaminenon-polymer478.65Chemie (E11)
5ASODIUM IONnon-polymer23.01Chemie (NA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight101524.3
Non-Polymers*Number of molecules7
Total formula weight3201.7
All*Total formula weight104726.0
*Water molecules are not included.

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PDB entries from 2024-04-24

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