5L2I
The X-ray co-crystal structure of human CDK6 and Palbociclib.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 6 | polymer | 307 | 35019.2 | 1 | UniProt (Q00534) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 6,Serine/threonine-protein kinase PLSTIRE |
| 2 | A | 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE | non-polymer | 447.5 | 1 | Chemie (LQQ) |
Sequence modifications
A: 1 - 301 (UniProt: Q00534)
| PDB | External Database | Details |
|---|---|---|
| His 302 | - | expression tag |
| His 303 | - | expression tag |
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35019.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 447.5 | |
| All* | Total formula weight | 35466.7 |
