5L2F
High Resolution Structure of Acinetobacter baumannii beta-lactamase OXA-51 I129L/K83D bound to doripenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Beta-lactamase | polymer | 250 | 28109.0 | 4 | UniProt (Q5QT35) Pfam (PF00905) In PDB | Acinetobacter baumannii | Beta-lactamase OXA-51,Class D beta-lactamase |
| 2 | A, B, C, D | (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 422.5 | 4 | Chemie (4J6) | |||
| 3 | A, C, D | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | A, B, C, D | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 871 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 26 - 274 (UniProt: Q5QT35)
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | initiating methionine |
| Asp 83 | Lys 83 | engineered mutation |
| Leu 129 | Ile 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112435.8 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2419.8 | |
| All* | Total formula weight | 114855.6 |
