5L21
Crystal structure of BoNT/A receptor binding domain in complex with VHH C2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Botulinum neurotoxin type A | polymer | 428 | 49877.5 | 1 | UniProt (A5HZZ9) Pfam (PF07953) Pfam (PF07951) UniProt (by SIFTS) (P0DPI1) | Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) | BoNT/A,Bontoxilysin-A,BOTOX |
| 2 | B (B) | VHH-C2 | polymer | 119 | 13326.8 | 1 | Vicugna pacos | ||
| 3 | C, D (A, B) | water | water | 18.0 | 566 | Chemie (HOH) |
Sequence modifications
A: 872 - 1296 (UniProt: A5HZZ9)
| PDB | External Database | Details |
|---|---|---|
| Gly 869 | - | cloning artifact |
| Pro 870 | - | cloning artifact |
| Met 871 | - | cloning artifact |
| Ala 1158 | Thr 1158 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63204.3 | |
| All* | Total formula weight | 63204.3 |
