5L1Z
TAR complex with HIV-1 Tat-AFF4-P-TEFb
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 9 | polymer | 330 | 38031.1 | 1 | UniProt (P50750) Pfam (PF00069) | Homo sapiens (Human) | C-2K,Cell division cycle 2-like protein kinase 4,Cell division protein kinase 9,Serine/threonine-protein kinase PITALRE,Tat-associated kinase complex catalytic subunit |
| 2 | B (B) | Cyclin-T1 | polymer | 264 | 30619.0 | 1 | UniProt (O60563) Pfam (PF00134) Pfam (PF21797) | Homo sapiens (Human) | Cyclin-T |
| 3 | C (C) | AF4/FMR2 family member 4 | polymer | 36 | 4130.7 | 1 | UniProt (Q9UHB7) | Homo sapiens | ALL1-fused gene from chromosome 5q31 protein,Protein AF-5q31,Major CDK9 elongation factor-associated protein |
| 4 | D (D) | Protein Tat | polymer | 58 | 6784.1 | 1 | UniProt (P69697) Pfam (PF00539) | Human immunodeficiency virus type 1 group M subtype B (isolate BH10) (HIV-1) | Transactivating regulatory protein |
| 5 | E (N) | RNA (5'-R(P*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*U)-3') | polymer | 23 | 7356.4 | 1 | Human immunodeficiency virus 1 | ||
| 6 | F, G (D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
D: 1 - 57 (UniProt: P69697)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 86921.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 87052.1 |
