5L1N

Pyrococcus horikoshii CoA Disulfide Reductase Quadruple Mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Coenzyme A disulfide reductase	polymer	453	49817.3	2	UniProt (O58308)	Pyrococcus horikoshii	CoADR
2	C, E (A, B)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
3	D, F (A, B)	COENZYME A	non-polymer		767.5	2	Chemie (COA)

Sequence modifications

A, B: 1 - 445 (UniProt: O58308)

PDB	External Database	Details
Ala 65	Tyr 65	engineered mutation
Ala 66	Tyr 66	engineered mutation
Gly 67	Pro 67	engineered mutation
Ala 367	His 367	engineered mutation
Leu 446	-	expression tag
Glu 447	-	expression tag
His 448	-	expression tag
His 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	99634.7
Non-Polymers*	Number of molecules	4
	Total formula weight	3106.2
All*	Total formula weight	102740.8

*Water molecules are not included.