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5L1L

PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dT site

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
In PDB
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2TDNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3')polymer123692.41synthetic construct
3PDNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3')polymer82426.61synthetic construct
4A2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidinenon-polymer466.21Chemie (0KX)
5AMAGNESIUM IONnon-polymer24.32Chemie (MG)
6AGLYCEROLnon-polymer92.13Chemie (GOL)
7waterwater18.0526Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54736.8
Non-Polymers*Number of molecules6
Total formula weight791.1
All*Total formula weight55527.8
*Water molecules are not included.

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PDB entries from 2024-04-17

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