5L1B

AMPA subtype ionotropic glutamate receptor GluA2 in Apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutamate receptor 2,Glutamate receptor 2	polymer	803	89805.7	4	UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Rat)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2	E, F, G, H (A, B, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)

Sequence modifications

A, B, C, D: 10 - 544 (UniProt: P19491)

PDB	External Database	Details
Glu 241	Asn 256	engineered mutation
Leu 382	Val 397	engineered mutation
-	Leu 399	deletion
-	Thr 400	deletion
-	Glu 401	deletion
-	Leu 402	deletion
-	Pro 403	deletion
-	Ser 404	deletion
Glu 384	Gly 405	engineered mutation
Asp 385	Asn 406	engineered mutation
Gln 392	Asn 413	engineered mutation

A, B, C, D: 567 - 826 (UniProt: P19491)

PDB	External Database	Details
Asp 564	-	linker
Thr 565	-	linker
Asp 566	-	linker
Ala 589	Cys 610	engineered mutation
Thr 744	Asn 765	engineered mutation
Pro 745	Ala 766	engineered mutation
Ser 754	Asn 775	engineered mutation
Val 758	Leu 779	engineered mutation
Ala 775	Ser 796	engineered mutation
Lys 776	Gly 797	engineered mutation
Asp 777	Gly 798	engineered mutation
Ser 778	Gly 799	engineered mutation
Gly 779	Asp 800	engineered mutation
Gly 827	-	expression tag
Leu 828	-	expression tag
Val 829	-	expression tag
Pro 830	-	expression tag
Arg 831	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	359222.9
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	360107.8

*Water molecules are not included.