5KZU
Crystal structure of an acetylcholine binding protein from Aplysia californica (Ac-AChBP) in complex with click chemistry compound 9-[[1-[8-methyl-8-(2-phenylethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]triazol-4-yl]methyl]carbazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Soluble acetylcholine receptor | polymer | 230 | 26212.1 | 5 | UniProt (Q8WSF8) Pfam (PF02931) | Aplysia californica (California sea hare) | |
| 2 | F, H, J, L, M (A, B, D, E) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | G, I (A, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 4 | K (D) | 9-[[1-[8-methyl-8-(2-phenylethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]triazol-4-yl]methyl]carbazole | non-polymer | 476.6 | 1 | Chemie (74S) | |||
| 5 | N, O, P, Q, R (A, B, C, D, E) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 219 (UniProt: Q8WSF8)
| PDB | External Database | Details |
|---|---|---|
| Asp -8 | - | expression tag |
| Tyr -7 | - | expression tag |
| Lys -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Lys -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Ser 220 | - | expression tag |
| Arg 221 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 131060.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1345.4 | |
| All* | Total formula weight | 132405.9 |
