5KY9
mouse POFUT1 in complex with mouse Notch1 EGF12 mutant (D464G/A465G) and GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GDP-fucose protein O-fucosyltransferase 1 | polymer | 355 | 40457.3 | 1 | UniProt (Q91ZW2) Pfam (PF10250) | Mus musculus (Mouse) | Peptide-O-fucosyltransferase 1,O-FucT-1 |
| 2 | B (B) | Neurogenic locus notch homolog protein 1 | polymer | 40 | 4361.8 | 1 | UniProt (Q01705) Pfam (PF12661) | Mus musculus (Mouse) | Notch 1,Motch A,mT14,p300 |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A: 33 - 384 (UniProt: Q91ZW2)
B: 452 - 491 (UniProt: Q01705)
| PDB | External Database | Details |
|---|---|---|
| Gly 30 | - | expression tag |
| Ala 31 | - | expression tag |
| Pro 32 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 464 | Asp 464 | engineered mutation |
| Gly 465 | Ala 465 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44819.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 664.4 | |
| All* | Total formula weight | 45483.5 |
