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5KY0

mouse POFUT1 in complex with mouse Notch1 EGF12(D464G) and GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GDP-fucose protein O-fucosyltransferase 1polymer35540457.31UniProt (Q91ZW2)
Pfam (PF10250)
Mus musculus (Mouse)Peptide-O-fucosyltransferase 1,O-FucT-1
2B
(B)
Neurogenic locus notch homolog protein 1polymer404375.91UniProt (Q01705)
Pfam (PF12661)
Mus musculus (Mouse)Notch 1,Motch A,mT14,p300
3C, D
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
4E
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
5F, G
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
6H, I
(A, B)
waterwater18.0479Chemie (HOH)
Sequence modifications
A: 33 - 384 (UniProt: Q91ZW2)
PDBExternal DatabaseDetails
Gly 30-expression tag
Ala 31-expression tag
Pro 32-expression tag
B: 452 - 491 (UniProt: Q01705)
PDBExternal DatabaseDetails
Gly 464Asp 464engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight44833.1
Non-Polymers*Number of molecules5
Total formula weight1069.8
All*Total formula weight45902.9
*Water molecules are not included.

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PDB entries from 2024-11-13

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