5KPM
Glycogen Synthase Kinase 3 beta Complexed with BRD3731
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycogen synthase kinase-3 beta | polymer | 424 | 47179.5 | 2 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (Human) | GSK-3 beta, Serine/threonine-protein kinase GSK3B |
| 2 | C, D (A, B) | (4~{S})-3-(2,2-dimethylpropyl)-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one | non-polymer | 377.5 | 2 | Chemie (6VM) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 420 (UniProt: P49841)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 94359.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 755.0 | |
| All* | Total formula weight | 95114.0 |
