5KOK
Pavine N-methyltransferase in complex with Tetrahydropapaverine and S-adenosylhomocysteine pH 7.25
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pavine N-methyltransferase | polymer | 397 | 46437.0 | 2 | UniProt (C3SBW0) Pfam (PF02353) | Thalictrum flavum subsp. glaucum (Yellow meadow rue) | PfPavNMT |
| 2 | C, F (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 3 | D, G (A, B) | (1~{S})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline | non-polymer | 343.4 | 2 | Chemie (S9T) | |||
| 4 | E, H (A, B) | (1~{R})-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline | non-polymer | 343.4 | 2 | Chemie (R9T) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 356 (UniProt: C3SBW0)
| PDB | External Database | Details |
|---|---|---|
| Met -40 | - | expression tag |
| Arg -39 | - | expression tag |
| Gly -38 | - | expression tag |
| Ser -37 | - | expression tag |
| His -36 | - | expression tag |
| His -35 | - | expression tag |
| His -34 | - | expression tag |
| His -33 | - | expression tag |
| His -32 | - | expression tag |
| His -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Met -29 | - | expression tag |
| Ala -28 | - | expression tag |
| Ser -27 | - | expression tag |
| Met -26 | - | expression tag |
| Thr -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Gln -22 | - | expression tag |
| Gln -21 | - | expression tag |
| Met -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Arg -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Leu -16 | - | expression tag |
| Tyr -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Lys -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Arg -8 | - | expression tag |
| Trp -7 | - | expression tag |
| Ile -6 | - | expression tag |
| Arg -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gln 0 | - | expression tag |
| Asp 224 | Tyr 224 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 92873.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2142.5 | |
| All* | Total formula weight | 95016.4 |
