5KNX

Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with {[(2-[(Hypoxanthin-9H-yl)methyl]propane-1,3-diyl)bis(oxy)]bis- (methylene)}diphosphonic Acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Hypoxanthine-guanine phosphoribosyltransferase	polymer	182	20643.9	2	UniProt (A0A0U4JN50) Pfam (PF00156) UniProt (by SIFTS) (P0A9M2)	Escherichia coli
2	C, E (A, B)	[2-[(6-oxidanylidene-1~{H}-purin-9-yl)methyl]-3-(phosphonomethoxy)propoxy]methylphosphonic acid	non-polymer		412.2	2	Chemie (6WC)
3	D, F, G (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	H, I (A, B)	water	water		18.0	205	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41287.7
Non-Polymers*	Number of molecules	5
	Total formula weight	897.4
All*	Total formula weight	42185.1

*Water molecules are not included.