5KMN
TrkA JM-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity nerve growth factor receptor | polymer | 330 | 37292.8 | 1 | UniProt (P04629) Pfam (PF07714) | Homo sapiens (Human) | Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA |
| 2 | B (A) | 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea | non-polymer | 386.4 | 1 | Chemie (6UK) | |||
| 3 | C (A) | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence modifications
A: 474 - 796 (UniProt: P04629)
| PDB | External Database | Details |
|---|---|---|
| Ace 0 | - | acetylation |
| His 797 | - | expression tag |
| His 798 | - | expression tag |
| His 799 | - | expression tag |
| His 800 | - | expression tag |
| His 801 | - | expression tag |
| His 802 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37292.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 386.4 | |
| All* | Total formula weight | 37679.2 |
