5KMM

TrkA JM-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-(1-naphthyl)urea

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	High affinity nerve growth factor receptor	polymer	329	37266.7	1	UniProt (P04629) Pfam (PF07714)	Homo sapiens (Human)	Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA
2	B (A)	1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-naphthalen-1-yl-urea	non-polymer		354.4	1	Chemie (6UJ)
3	C (A)	water	water		18.0	43	Chemie (HOH)

Sequence modifications

A: 474 - 796 (UniProt: P04629)

PDB	External Database	Details
His 797	-	expression tag
His 798	-	expression tag
His 799	-	expression tag
His 800	-	expression tag
His 801	-	expression tag
His 802	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37266.7
Non-Polymers*	Number of molecules	1
	Total formula weight	354.4
All*	Total formula weight	37621.2

*Water molecules are not included.