5KML
TrkA JM-kinase with 1-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | High affinity nerve growth factor receptor | polymer | 330 | 37292.8 | 1 | UniProt (P04629) Pfam (PF07714) In PDB | Homo sapiens (Human) | Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA |
2 | A | 1-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea | non-polymer | 375.3 | 1 | Chemie (6UH) | |||
3 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 474 - 796 (UniProt: P04629)
PDB | External Database | Details |
---|---|---|
Ace 0 | - | acetylation |
His 797 | - | expression tag |
His 798 | - | expression tag |
His 799 | - | expression tag |
His 800 | - | expression tag |
His 801 | - | expression tag |
His 802 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37292.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 375.3 | |
All* | Total formula weight | 37668.1 |