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5KMG

Near-atomic cryo-EM structure of PRC1 bound to the microtubule

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tubulin alpha-1B chainpolymer44149095.41UniProt (Q2XVP4)
Pfam (PF00091)
Pfam (PF03953)
Sus scrofa (Pig)Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2B
(B)
Tubulin beta chainpolymer43148299.31UniProt (P02554)
Pfam (PF00091)
Pfam (PF03953)
Sus scrofa (Pig)Beta-tubulin
3C
(P)
Protein regulator of cytokinesis 1polymer12815693.91UniProt (O43663)Homo sapiens (Human)
4D
(A)
GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
5E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6F
(B)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
7G
(B)
Peloruside Anon-polymer548.71Chemie (POU)
Sequence modifications
P: 341 - 464 (UniProt: O43663)
PDBExternal DatabaseDetails
Gly 337-expression tag
Ala 338-expression tag
Ala 339-expression tag
Ala 340-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight113088.7
Non-Polymers*Number of molecules4
Total formula weight1539.3
All*Total formula weight114628.0
*Water molecules are not included.

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PDB entries from 2025-06-11

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