5KM8
Human Histidine Triad Nucleotide Binding Protein 2 (hHint2) Cidofovir complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histidine triad nucleotide-binding protein 2, mitochondrial | polymer | 142 | 15221.3 | 2 | UniProt (Q9BX68) Pfam (PF01230) | Homo sapiens (Human) | HINT-2,HINT-3,HIT-17kDa |
| 2 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | E (B) | ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid | non-polymer | 279.2 | 1 | Chemie (L8P) | |||
| 5 | F, G (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | H (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | I, J (A, B) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 163 (UniProt: Q9BX68)
| PDB | External Database | Details |
|---|---|---|
| Ser 22 | - | expression tag |
| Asn 23 | - | expression tag |
| Ala 24 | - | expression tag |
| Met 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30442.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 609.0 | |
| All* | Total formula weight | 31051.7 |
