5KJL
SMYD2 in complex with AZ378
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | N-lysine methyltransferase SMYD2 | polymer | 429 | 49343.6 | 1 | UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) In PDB | Homo sapiens (Human) | HSKM-B,Histone methyltransferase SMYD2,Lysine N-methyltransferase 3C,SET and MYND domain-containing protein 2 |
| 2 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A: 5 - 433 (UniProt: Q9NRG4)
| PDB | External Database | Details |
|---|---|---|
| Glu 165 | Gly 165 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49343.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 594.7 | |
| All* | Total formula weight | 49938.2 |
