5KJC
V222I horse liver alcohol dehydrogenase complexed with NAD+ and pentafluorobenzyl alcohol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alcohol dehydrogenase E chain | polymer | 374 | 39867.3 | 2 | UniProt (P00327) Pfam (PF08240) Pfam (PF00107) | Equus caballus (Horse) | |
| 2 | C, D, K, L (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, M (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) | non-polymer | 663.4 | 2 | Chemie (NAJ) | |||
| 4 | F, N (A, B) | 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL | non-polymer | 198.1 | 2 | Chemie (PFB) | |||
| 5 | G, H, I, J, O (A, B) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 5 | Chemie (MRD) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 902 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 374 (UniProt: P00327)
| PDB | External Database | Details |
|---|---|---|
| Ile 222 | Val 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79734.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2575.5 | |
| All* | Total formula weight | 82310.1 |
