5KIZ
Solution Structure of a repacked version of HIF-2 alpha PAS-B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endothelial PAS domain-containing protein 1 | polymer | 114 | 13264.1 | 1 | UniProt (Q99814) Pfam (PF14598) | Homo sapiens (Human) | EPAS-1,Basic-helix-loop-helix-PAS protein MOP2,Class E basic helix-loop-helix protein 73,bHLHe73,HIF-1-alpha-like factor,HLF,Hypoxia-inducible factor 2-alpha,HIF2-alpha,Member of PAS protein 2,PAS domain-containing protein 2 |
Sequence modifications
A: 239 - 349 (UniProt: Q99814)
| PDB | External Database | Details |
|---|---|---|
| Gly 236 | - | expression tag |
| Glu 237 | - | expression tag |
| Phe 238 | - | expression tag |
| Phe 248 | His 248 | engineered mutation |
| Ser 278 | Tyr 278 | engineered mutation |
| Trp 281 | Tyr 281 | engineered mutation |
| Met 323 | Gly 323 | engineered mutation |
| Ala 339 | Cys 339 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13264.1 | |
| All* | Total formula weight | 13264.1 |
