5KGF
Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.2 | polymer | 136 | 15421.1 | 2 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | Histone H3 |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11439.5 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | Histone H4Kc20me2 |
| 3 | C, G (C, G) | Histone H2A type 1 | polymer | 130 | 14163.5 | 2 | UniProt (P0C0S8) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (Human) | H2A.1, Histone H2A/p |
| 4 | D, H (D, H) | Histone H2B type 1-C/E/F/G/I | polymer | 126 | 13937.2 | 2 | UniProt (P62807) Pfam (PF00125) | Homo sapiens (Human) | Histone H2B.1 A, Histone H2B.a, H2B/a, Histone H2B.g, H2B/g, Histone H2B.h, H2B/h, Histone H2B.k, H2B/k, Histone H2B.l, H2B/l |
| 5 | I (I) | DNA (145-MER) | polymer | 145 | 44520.4 | 1 | synthetic construct | ||
| 6 | J (J) | DNA (145-MER) | polymer | 145 | 44991.7 | 1 | synthetic construct | ||
| 7 | K, N (L, K) | Tumor suppressor p53-binding protein 1 | polymer | 21 | 2376.8 | 2 | UniProt (H7BZY0) UniProt (by SIFTS) (Q12888) | Homo sapiens (Human) | |
| 8 | L, M (O, M) | Ubiquitin | polymer | 76 | 8576.8 | 2 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) |
Sequence modifications
C, G: 0 - 129 (UniProt: P0C0S8)
| PDB | External Database | Details |
|---|---|---|
| Arg 13 | Lys 14 | engineered mutation |
| Ser 16 | Thr 17 | engineered mutation |
| Arg 36 | Lys 37 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 221341.9 | |
| All* | Total formula weight | 221341.9 |
