5KGE
Crystal structure of PIM1 with inhibitor: 5-(3,4-dichlorophenyl)-1~{H}-pyrazol-3-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 276 | 31905.2 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (Human) | |
| 2 | B, C, D, E, F... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
| 3 | Q (A) | 5-(3,4-dichlorophenyl)-1~{H}-pyrazol-3-amine | non-polymer | 228.1 | 1 | Chemie (6SN) | |||
| 4 | R, S (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | T (A) | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31905.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1351.2 | |
| All* | Total formula weight | 33256.4 |
