5KFX
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 300s
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase eta | polymer | 435 | 48531.6 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) | Homo sapiens (Human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | B (T) | DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3') | polymer | 12 | 3637.4 | 1 | Homo sapiens | ||
| 3 | C (P) | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3') | polymer | 9 | 2739.8 | 1 | Homo sapiens | ||
| 4 | D, F, M (A, P) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | G, H, I (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | J (A) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 1 | Chemie (DTP) | |||
| 8 | K (A) | DIPHOSPHATE | non-polymer | 173.9 | 1 | Chemie (DPO) | |||
| 9 | L (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 10 | N, O, P (A, T, P) | water | water | 18.0 | 467 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 61 | Arg 61 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54908.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1093.5 | |
| All* | Total formula weight | 56002.3 |
