5KFQ
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 10 mM Mn2+ for 600s
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA polymerase eta | polymer | 435 | 48617.7 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) In PDB | Homo sapiens (Human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | T | DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3') | polymer | 12 | 3637.4 | 1 | Homo sapiens | ||
| 3 | P | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*(AS))-3') | polymer | 9 | 2755.9 | 1 | Homo sapiens | ||
| 4 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | A | 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE) | non-polymer | 507.2 | 1 | Chemie (STP) | |||
| 8 | A | DIPHOSPHATE | non-polymer | 173.9 | 1 | Chemie (DPO) | |||
| 9 | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 55011.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1107.4 | |
| All* | Total formula weight | 56118.4 |
