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5KFK

Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 300s

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer123637.41Homo sapiens
3C
(P)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3')polymer92739.81Homo sapiens
4D, F, L
(A, P)
MANGANESE (II) IONnon-polymer54.93Chemie (MN)
5E
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
6G, H, I
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
7J
(A)
2'-DEOXYADENOSINE 5'-TRIPHOSPHATEnon-polymer491.21Chemie (DTP)
8K
(A)
DIPHOSPHATEnon-polymer173.91Chemie (DPO)
9M, N, O
(A, T, P)
waterwater18.0462Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54994.9
Non-Polymers*Number of molecules9
Total formula weight1146.3
All*Total formula weight56141.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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