5KDR
The crystal structure of carboxyltransferase from Staphylococcus Aureus bound to the antimicrobial agent moiramide B.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | polymer | 327 | 36684.7 | 1 | UniProt (Q2FG38) Pfam (PF03255) UniProt (by SIFTS) (Q2FXM7) In PDB | Staphylococcus aureus (strain USA300) | Acetyl-CoA carboxylase carboxyltransferase subunit alpha |
2 | B | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | polymer | 285 | 31916.8 | 1 | UniProt (Q2YTE0) Pfam (PF17848) Pfam (PF01039) UniProt (by SIFTS) (Q2FXM6) In PDB | Staphylococcus aureus (strain bovine RF122 / ET3-1) | Acetyl-CoA carboxylase carboxyltransferase subunit beta |
3 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
4 | B | Moiramide B | non-polymer | 453.5 | 1 | Chemie (YT5) | |||
5 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
6 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
7 | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
A: 1 - 314 (UniProt: Q2FG38)
PDB | External Database | Details |
---|---|---|
Met -12 | - | initiating methionine |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
Leu -5 | - | expression tag |
Val -4 | - | expression tag |
Pro -3 | - | expression tag |
Arg -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68601.5 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 869.2 | |
All* | Total formula weight | 69470.7 |