5KDF
Inorganic pyrophosphatase from Mycobacterium tuberculosis in complex with inhibitor 6 and inorganic pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inorganic pyrophosphatase | polymer | 171 | 19454.9 | 1 | UniProt (P9WI55) Pfam (PF00719) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Pyrophosphate phospho-hydrolase,PPase |
| 2 | B (A) | ~{N}2,~{N}2,~{N}4,~{N}4-tetramethyl-6-(1-phenylpyrrol-2-yl)-1,3,5-triazine-2,4-diamine | non-polymer | 308.4 | 1 | Chemie (6RU) | |||
| 3 | C, D, E (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 4 | F (A) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 5 | G (A) | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 1 - 162 (UniProt: P9WI55)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| Ala -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19454.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 604.6 | |
| All* | Total formula weight | 20059.4 |
