5KAJ

Crystal structure of a dioxygenase in the Crotonase superfamily in P21, A319C mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase	polymer	438	48273.2	12	UniProt (Q8KLK7) Pfam (PF00378) In PDB	Streptomyces toyocaensis
2	A, B, C, D, E...	[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[(~{E})-2-[3,5-bis(oxidanyl)phenyl]-1-oxidanyl-ethenyl]sulfanylethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate	non-polymer		917.7	12	Chemie (YE2)
3		water	water		18.0	1011	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 438 (UniProt: Q8KLK7)

PDB	External Database	Details
Cys 319	Ala 319	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	579278.3
Non-Polymers*	Number of molecules	12
	Total formula weight	11012.0
All*	Total formula weight	590290.3

*Water molecules are not included.