5KA6

HIV-1 gp41 variant Q552R and L555M resistance mutations

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Transmembrane protein gp41	polymer	91	10632.9	3	UniProt (P04578) Pfam (PF00517)	Human immunodeficiency virus type 1 (HIV-1)	Glycoprotein 41
2	D, E, F (A, B, C)	water	water		18.0	96	Chemie (HOH)

Sequence modifications

A, B, C: 543 - 619 (UniProt: P04578)

PDB	External Database	Details
Met 542	-	initiating methionine
Arg 552	Gln 552	engineered mutation
Met 555	Leu 555	engineered mutation

A, B, C: 625 - 661 (UniProt: P04578)

PDB	External Database	Details
Gly 620	-	linker
Gly 621	-	linker
Arg 622	-	linker
Gly 623	-	linker
Gly 624	-	linker
Gly 662	-	expression tag
Gly 663	-	expression tag
His 664	-	expression tag
His 665	-	expression tag
His 666	-	expression tag
His 667	-	expression tag
His 668	-	expression tag
His 669	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	31898.8
All*	Total formula weight	31898.8

*Water molecules are not included.