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5KA4

Protein Tyrosine Phosphatase 1B T178A mutant, open state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 1polymer30635514.51UniProt (P18031)
Pfam (PF00102)
Homo sapiens (Human)Protein-tyrosine phosphatase 1B,PTP-1B
2B
(A)
waterwater18.080Chemie (HOH)
Sequence modifications
A: 1 - 301 (UniProt: P18031)
PDBExternal DatabaseDetails
Gly -4-expression tag
His -3-expression tag
Met -2-expression tag
Ala -1-expression tag
Ser 0-expression tag
Ala 178Thr 178engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35514.5
All*Total formula weight35514.5
*Water molecules are not included.

246333

PDB entries from 2025-12-17

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