5K8K

Structure of the Haemophilus influenzae LpxH-lipid X complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	UDP-2,3-diacylglucosamine hydrolase	polymer	256	30516.0	1	UniProt (P44046) Pfam (PF00149)	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	UDP-2,3-diacylglucosamine diphosphatase
2	B, C (A)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	D (A)	(R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE	non-polymer		711.9	1	Chemie (LP5)
4	E, F (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
5	G, H (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	I (A)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A: 2 - 237 (UniProt: P44046)

PDB	External Database	Details
Mse 1	-	initiating methionine
Leu 238	-	expression tag
Glu 239	-	expression tag
Glu 240	-	expression tag
Asn 241	-	expression tag
Leu 242	-	expression tag
Tyr 243	-	expression tag
Phe 244	-	expression tag
Gln 245	-	expression tag
Ser 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	30516.0
Non-Polymers*	Number of molecules	7
	Total formula weight	1124.0
All*	Total formula weight	31640.0

*Water molecules are not included.