5K7L
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Potassium voltage-gated channel subfamily H member 1 | polymer | 857 | 97359.8 | 1 | UniProt (Q63472) Pfam (PF13426) Pfam (PF00520) Pfam (PF07885) Pfam (PF00027) | Rattus norvegicus (Rat) | Voltage-gated potassium channel Eag1, Ether-a-go-go potassium channel 1, r-eag, Voltage-gated potassium channel subunit Kv10.1 |
| 2 | B (B) | Calmodulin | polymer | 149 | 16852.5 | 1 | UniProt (P62158) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) | Homo sapiens (Human) | CaM |
| 3 | C (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | D (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) |
Sequence modifications
A: 1 - 773 (UniProt: Q63472)
A: 774 - 848 (UniProt: Q63472)
A: 774 - 848 (UniProt: Q63472)
| PDB | External Database | Details |
|---|---|---|
| Ser 849 | - | expression tag |
| Asn 850 | - | expression tag |
| Ser 851 | - | expression tag |
| Leu 852 | - | expression tag |
| Glu 853 | - | expression tag |
| Val 854 | - | expression tag |
| Leu 855 | - | expression tag |
| Phe 856 | - | expression tag |
| Gln 857 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114212.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 707.9 | |
| All* | Total formula weight | 114920.2 |
