5K7I

IRAK4 in complex with AZ3864

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Interleukin-1 receptor-associated kinase 4	polymer	301	33876.2	2	UniProt (Q9NWZ3) Pfam (PF07714) In PDB	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	A, B	(3~{a}~{R},7~{a}~{S})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one	non-polymer		452.6	2	Chemie (6QZ)
3	B	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4		water	water		18.0	77	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67752.4
Non-Polymers*	Number of molecules	3
	Total formula weight	1001.2
All*	Total formula weight	68753.7

*Water molecules are not included.