5K7G

IRAK4 in complex with AZ3862

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Interleukin-1 receptor-associated kinase 4	polymer	301	33876.2	4	UniProt (Q9NWZ3) Pfam (PF07714)	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	E, F, H, I, L (A, B, D)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	G, J, K, M (A, B, C, D)	(3~{a}~{S},7~{a}~{R})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-one	non-polymer		452.6	4	Chemie (6R0)
4	N, O, P, Q (A, B, C, D)	water	water		18.0	313	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135504.9
Non-Polymers*	Number of molecules	9
	Total formula weight	2290.7
All*	Total formula weight	137795.5

*Water molecules are not included.