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5K7G

IRAK4 in complex with AZ3862

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DInterleukin-1 receptor-associated kinase 4polymer30133876.24UniProt (Q9NWZ3)
Pfam (PF07714)
In PDB
Homo sapiens (Human)IRAK-4,Renal carcinoma antigen NY-REN-64
2A, B, DSULFATE IONnon-polymer96.15Chemie (SO4)
3A, B, C, D(3~{a}~{S},7~{a}~{R})-1-methyl-5-[4-[[5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3,3~{a},4,6,7,7~{a}-hexahydropyrrolo[3,2-c]pyridin-2-onenon-polymer452.64Chemie (6R0)
4waterwater18.0313Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight135504.9
Non-Polymers*Number of molecules9
Total formula weight2290.7
All*Total formula weight137795.5
*Water molecules are not included.

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PDB entries from 2024-07-24

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