5K76

IRAK4 in complex with Compound 28

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Interleukin-1 receptor-associated kinase 4	polymer	301	33876.2	2	UniProt (Q9NWZ3) Pfam (PF07714) In PDB	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	A, B	~{N}-(4-morpholin-4-ylcyclohexyl)-5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine	non-polymer		385.5	2	Chemie (6R1)
3		water	water		18.0	47	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67752.4
Non-Polymers*	Number of molecules	2
	Total formula weight	771.0
All*	Total formula weight	68523.4

*Water molecules are not included.