5K75

IRAK4 in complex with Compound 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Interleukin-1 receptor-associated kinase 4	polymer	301	33876.2	4	UniProt (Q9NWZ3) Pfam (PF07714)	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	E, I, L, O (A, B, C, D)	~{N}1-(7,8-dihydro-6~{H}-cyclopenta[2,3]thieno[2,4-~{c}]pyrimidin-1-yl)-~{N}4,~{N}4-dimethyl-cyclohexane-1,4-diamine	non-polymer		316.5	4	Chemie (6QX)
3	F, G, H, J, K... (B, C, D)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
4	P, Q, R, S (A, B, C, D)	water	water		18.0	406	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135504.9
Non-Polymers*	Number of molecules	11
	Total formula weight	1938.3
All*	Total formula weight	137443.2

*Water molecules are not included.