5K72

IRAK4 in complex with Compound 21

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Interleukin-1 receptor-associated kinase 4	polymer	301	33876.2	4	UniProt (Q9NWZ3) Pfam (PF07714)	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	E, F, H, I, J (A, B)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	G, K, L, M (A, B, C, D)	~{N}4,~{N}4-dimethyl-~{N}1-[5-(oxan-4-yl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]cyclohexane-1,4-diamine	non-polymer		343.5	4	Chemie (6QY)
4	N, O, P, Q (A, B, C, D)	water	water		18.0	291	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135504.9
Non-Polymers*	Number of molecules	9
	Total formula weight	1854.2
All*	Total formula weight	137359.0

*Water molecules are not included.