5K6J
Human Phospodiesterase 4B in complex with pyridyloxy-benzoxaborole based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | polymer | 323 | 37313.3 | 1 | UniProt (Q07343) Pfam (PF00233) | Homo sapiens (Human) | DPDE4,PDE32 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | 6-[[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-trien-3-yl]oxy]-5-chloranyl-2-(4-oxidanylidenepentoxy)pyridine-3-carbonitrile | non-polymer | 403.6 | 1 | Chemie (6QQ) | |||
| 5 | E, F, G, H, I... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
| 6 | V (A) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37313.3 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 38861.8 |
