5K6E
Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with SBI0654919
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nuclear receptor ROR-gamma | polymer | 247 | 28721.3 | 2 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | C, D (A, B) | 2-chloranyl-6-fluoranyl-~{N}-[(2~{R})-4-(4-fluorophenyl)sulfonyl-2-(hydroxymethyl)-2,3-dihydro-1,4-benzoxazin-6-yl]benzamide | non-polymer | 494.9 | 2 | Chemie (6QP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B: 265 - 507 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 261 | - | expression tag |
| Ser 262 | - | expression tag |
| His 263 | - | expression tag |
| Met 264 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57442.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 989.8 | |
| All* | Total formula weight | 58432.4 |
