5K6B
Crystal structure of prefusion-stabilized RSV F single-chain 9 DS-Cav1 variant.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Fusion glycoprotein F0 | polymer | 447 | 49473.3 | 1 | UniProt (P03420) Pfam (PF00523) | Human respiratory syncytial virus A | Protein F |
| 2 | B (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | C, D, E, F (F) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G (F) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
F: 26 - 105 (UniProt: P03420)
F: 145 - 509 (UniProt: P03420)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Pro 102 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 143 | - | linker |
| Ser 144 | - | linker |
| Cys 155 | Ser 155 | engineered mutation |
| Phe 190 | Ser 190 | engineered mutation |
| Leu 207 | Val 207 | engineered mutation |
| Cys 290 | Ser 290 | engineered mutation |
| Arg 373 | Leu 373 | engineered mutation |
| Val 379 | Ile 379 | engineered mutation |
| Val 447 | Met 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49473.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 605.5 | |
| All* | Total formula weight | 50078.8 |
