5K4X
M. thermoresistible IMPDH in complex with IMP and Compound 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | polymer | 389 | 39854.5 | 1 | UniProt (A0A100XBM0) Pfam (PF00478) UniProt (by SIFTS) (G7CNL4) | Mycobacterium thermoresistibile | |
| 2 | B (A) | ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide | non-polymer | 291.3 | 1 | Chemie (6Q9) | |||
| 3 | C (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) | |||
| 4 | D (A) | water | water | 18.0 | 349 | Chemie (HOH) |
Sequence modifications
A: 3 - 110 (UniProt: A0A100XBM0)
A: 113 - 389 (UniProt: A0A100XBM0)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 111 | - | linker |
| Gly 112 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39854.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 639.5 | |
| All* | Total formula weight | 40494.0 |
